louvpfep

My most influential ICs

first_imgICM7218 antedeluvian says: LM339 October 25, 2016 at 3:37 pm Leave a Reply Cancel reply You must Register or Login to post a comment. This site uses Akismet to reduce spam. Learn how your comment data is processed. MAX690 October 6, 2016 at 9:42 am 8 thoughts on “My most influential ICs” LM358 LOC110 October 25, 2016 at 9:28 pm Log in to Reply MAX232 Share this:TwitterFacebookLinkedInMoreRedditTumblrPinterestWhatsAppSkypePocketTelegram Tags: Analog October 6, 2016 at 12:59 pm Log in to Reply Continue Reading Previous Using static analysis to improve IIoT device securityNext The Write Stuff: A Hot Date “@Timnn”did you mean the MC146818 RTC? “nnYes I did. Thanks for the info.n” Log in to Reply “@JackPeacocknn”I’d add the General Instruments AY-3-1015 async serial transceiver”nnI guess you’d have to add a Baud Rate generator to that. What part would you use- the Fairchild 4702?nn”lowly 2N3904 and 2N3906 transistors “. nnIt didn’t occu AD626 TL431 October 5, 2016 at 10:04 pm I had worked with several standalone UARTs and used several offerings like Intel’s 8251, but when National (or maybe it was Western Digital) brought out the INS8250, it seemed to cover every option (including an on-board oscillator and baud rate generator) except one. It didn’t have the 8051’s 9-bit mode. Still it was good enough to be in the PC. I actually wrote a design idea on how to manipulate the 8250 to achieve a 9-bit performance – it was published in EDN Design Ideas as” Implement a Nine-Data-Bit UART on a PC” in June 6, 1998, but good luck finding it. [Editor’s note: Although various system migrations have made finding gems such as this difficult, a portion at least of Aubrey’s article is here (scroll to the bottom).] As I started working more and more with RS485, the appearance of the MAX485 was a great improvement over the earlier devices. Although the TI SN75176 was nominally the same functionality as the MAX485, it was not implemented in CMOS and drew quite a bit more current. Perhaps it deserves the nod.Strangely enough, driving many LEDs (both discrete and as 7 segments) popped up quite often and the micros had a limited number of pins, not to mention fairly slow clock rates so that there were constraints on processing tasks. I found Intersil’s ICM7218 (and later Maxim’s equivalent) family worked its way into several designs especially since it had a serial interface, which was relatively unusual back then. The family is still going strong as you can see from a new Arduino Display Driver Shield from Maxim.Figure 1. The 72 LEDs just to the left of the middle of the board were driven by an ICM7218, the IC just below them. There is another favourite IC on the board – the 8032 (8051 derivative) and a linear regulator on the left with the heatsink although I can’t remember why. The unit worked from the telecommunications standard -48VDC and used a SMPS module (in the unpopulated area on the left). (Source: Author)  And for something completely different: years ago I was told that it was not possible to design a self-powered 4-20 current loop isolator. I stumbled across a linear opto-isolator the LOC110 from CP Clare (now IXYS) (an alternate to the IL300 from Siemens at the time) and started working with it in my spare time. In the end it could be done and I am told my product is now considered the industry standard and has been for over 17 years. I first used the Linear Tech op-amp LT1366 on this loop isolator. For a digital designer flirting with analog, I chose the most all-round op-amp that I could find. Low power, rail-to-rail and operating to over 24Vdc supply, it may be pricey, but it worked like a charm and it frequently sneaks into my designs even though there may be a more optimal choice for a specific case.There are two kinds of design engineers in industrial electronics: those who know about instrumentation amplifiers (IA) and those who are about to learn that they needed an IA and what the heck are they going to do about it now? Planet Analog editor, Steve Taranovich, recently did a blog on the topic “6 Burr-Brown secrets to success you need to know about instrumentation amplifiers”. I messed around with a few in my early days, even tried to make my own from three op-amps. I quickly settled on the AD626 from Analog Devices. It will work with a single supply voltage, from low to high supply voltages and will tolerate a common mode voltage outside the supply rails, making it suitable for high side current monitoring. Even though there are many more options in the marketplace today, it is still a favourite of mine.I have designed more 4-to-20mA output devices that the proverbial number of hot dinners I have consumed. Where there is no requirement for loop power, the XTR110 is the quickest and surest way of designing the output. It doesn’t hurt that it has great performance as well even though today there are more economical options.It’s amazing how long some of these devices have been in production. There is no real order in my list, so please don’t try to read anything into the sequence. It’s your turn now. What devices have made a difference to the way you approach a design?My List with links: Log in to Reply XTR110 MAX485 RGARVIN640 says: “@RGARVIN640nnMy electronic formative years were in South Africa which was far removed from any other epicentre of electronic design and the market was also significantly different. Intel had great representation followed at quite a distance by Motorola. antedeluvian says: center_img Log in to Reply 2716 “DavidnnThere is no dispute about the influence of the 741- it just wasn’t a direct influence on my designs. nnHowever indirectly it did influence me a lot. I did a design once for a coffee packaging machine that measured weight using LVDTs. The gain s INS8250 Tim Hawks says: “No mention of the 741? It may be a pretty ordinary op-amp compared to your AD626, but it was the first real universal op-amp (the 709 was finnicky to compensate) and a lot of us cut our teeth on it. That makes it influential in my book…” JackPeacock says: October 16, 2016 at 12:17 am “For number 13 did you mean the MC146818 RTC? It’s data sheet at least is now at NXP, via Freescale from Motorola” LT1366 “I’d add the General Instruments AY-3-1015 async serial transceiver, the original UART and the go-to part for RS-232 interfaces.nnAnd how many times did the lowly 2N3904 and 2N3906 transistors make it onto a board to switch that one last signal?” MC6818 October 5, 2016 at 9:03 pm ICL7660 PSoC antedeluvian says: 8051 “Mine was the 6502 chip from Synertek in 1980. It was lower priced than other available 8 bit micros at the time and opened up many different applications to micro control. There were also several other manufacturers who were making the part which helped k David_Ashton_EC says: October 15, 2016 at 11:44 pm 7805 LM317 At the turn of the 21st century several EE luminaries created lists for a Hall of Fame of ICs. I searched, but could find no official list. I was reminded of it in a comment by Martin Rowe “MAX232 is a hall-of-fame IC. I designed them into a number of products, including the first Extech Comms printer ”. I thought I should create my own Hall of Fame. There are some that I am sure we can all agree should be there. Others have special meaning to me in that they proved to be really useful and appeared in several projects, often defining the approach.There can be no doubt that the 555 should be on anyone’s list. An analog IC that pretends to be digital, can be configured as an astable or monostable and is simple enough for a beginner or even a dumb digital engineer like me. The market segment still seems to be remarkably vibrant (see my blog “Timer, anyone?”)Early on, MOS micros, EPROMs, and RAMs had multi voltage supplies and they drew a fair amount of current, so heat dissipation from linear supplies (switch mode power supplies were few and far between) was an issue. Micros and RAM had already shifted to a 5V only supply, but when Intel introduced the 2716 (2Kx8) EPROM systems could be completely single supply. What a win! And yet we have now returned to multiple supplies!The Hitachi range of dot matrix LCD character displays using the HD44780 controller came in many formats from 1 line by 8 characters to 2 lines by 32 characters. They were great for a user interface when micro-based devices were still in their infancy. Whilst the HD44780 is a candidate on its own for Hall of Fame, I have an associated IC: The LCD module required a negative voltage to alter the viewing angle of the display and since I wanted a just a single supply board, Intersil’s ICL7660 was the answer to this problem and several other issues that required low current negative voltages.There have been many iterations to the switched capacitor approach of the ICL7660, higher voltage, smaller capacitors, positive voltage, smaller size but perhaps the most famous of the offshoots was the MAX232. Since I began this blog with Martin’s quote, I need not continue.When I was designing SBX cards (mezzanine cards intended for Intel’s single board computer (Multibus) product range) I designed and produced a watchdog timer which consisted of several TTL ICs. I remember going to the first Maxim seminar (Maxim had just been formed as a spin off from Intersil) and learning about the MAX232 and the MAX690 watchdog timer. I was really enthused after that and almost every system of mine since then has employed a watchdog timer.As you can see above, single supply voltage drove much of the design considerations. In the early days I was also very wary of analog circuits and had a mental block on the bipolar voltages used on the linear devices. And then suddenly there were the LM311/ LM339 single and quad comparators and there was light. It took a while longer for the single supply op-amp like the LM358 to come out, but when it did I found myself working more and more with analog circuits. The TL431 voltage reference has also graced many of my designs.Still sticking with the single supply theme, who could forget the linear regulators – the LM309, the 7805, and the adjustable LM317? If I remember correctly, the LM317 was selected as the electronic product of the year when it was released.When it came to micros I designed with quite a few: the 8085, Z80, 8048 and the 8051, but if I have to select just one then it would have to be the 8051. But I hasten to add that when I discovered the PSoC architecture circa 2002, there has been no other architecture that I will use if given free reign. It is true that the implementation has undergone a radical shift from the PSoC1 to PSoC4 and PSoC5, but it is for the better and I really enjoy building as much of the design into the hardware capabilities of the device. Take a look at my recent 3 part blog on how to measure the RMS of a signal “Measuring an RMS value on a PSoC5” Part 1, Part 2 and Part 3.I was always interested in clock/calendar devices and it seemed to me that they took a long time to come out in monolithic form. I made and early SBX board using the NEC uPD1990 which was a Julian calendar and needed software to add the leap day. National Semi had announced several, but when I tried to get them I was told by the salesman that it was “easy to invent a data sheet, but harder to make the device”. When Motorola brought out the MC6818 it seemed to encapsulate all that I needed and my choice was validated by IBM’s selection of it for the PC.Continue to page 2 >> antedeluvian says: Log in to Reply 555 Log in to Reply Log in to Reply last_img read more

Read More

Disha Patani savagely trolled for fake dress after Janhvi steps out in original

first_imgThe world of fashion is not an easy one to navigate through. Especially with Instagram policing accounts like Diet Sabya around, it is impossible for even the smallest fashion mistake to go unnoticed.Diet Sabya, and Instagram account who calls out designers and celebrities for copying or doning fake copies of luxury brands does not spare anyone. Right from Anushka Sharma to Shweta Bachchan, the anonymous account calls out anyone who knowingly or unknowingly sports a fake.And their most recent target is Disha Patani. A recent post on the page shows Disha Patani wearing a white summer dress, which is apparently a fake version of a dress from Daisy.The problem arose when Janhvi Kapoor apparently wore the original Daisy dress and that came to Diet Sabya’s notice.Check out the post:Well, even though the dresses do look quite similar, who’s to say whether Disha’s dress was actually intended to be a copy of Daisy or it was plain coincidence.ALSO SEE | Ishaan Khatter is floored by huge birthday cake. Janhvi can’t stop smilingALSO SEE | Disha Patani shares kickass kickboxing workout videoALSO WATCH | Ishaan Khatter says Janhvi made me a foodielast_img read more

Read More

Debt-ridden Ronaldinho in trouble over unpaid environmental fines

first_imgA court in southern Brazil has forbidden ex-Barcelona striker Ronaldinho from selling 57 of his real estate properties due to an unpaid environmental fine and other debts, a Brazilian newspaper reported on Monday.The Folha de S.Paulo paper said the former World Player of the Year owes 9.5 million reais ($2.51 million) in unpaid environmental fines after illegally building a pier at his lake house in Porto Alegre.Creditors have also taken action to recover 7.8 million reais in other debts, Folha said.Authorities have confiscated Ronaldinho’s passport until the cases are resolved, the newspaper added.The judge in Porto Alegre told Reuters the case fell under judicial secrecy rules and would not confirm or deny any details about the newspaper report.Ronaldinho’s lawyer denied the player’s assets were under restriction but told Folha de S.Paulo he could not comment on the details of the case because of the judicial secrecy ruling.The 39-year-old striker retired from football in 2015 after spells with a host of clubs in Brazil and Europe.He was twice voted FIFA player of the year while playing for Barcelona and he also won the World Cup with Brazil in 2002.last_img read more

Read More

Wenger admits Arsenal have no title target

first_imgArsenal Wenger admits Arsenal have no title target Chris Burton Last updated 1 year ago 08:26 12/9/17 FacebookTwitterRedditcopy Comments(1) Arsenal Arsene Wenger Getty Images Arsenal Premier League Arsène Wenger The Gunners boss concedes that his side are too far adrift at present to be considering a tilt at the Premier League crown in the 2017-18 campaign Arsene Wenger admits talk of a Premier League title challenge from Arsenal is “not realistic”.The 2017-18 campaign is only 15 games old, but the Gunners are already prepared to focus on other areas.Wenger’s side sit 15 points adrift of leaders Manchester City at present, with a 3-1 defeat to Manchester United dropping them into fifth spot. Article continues below Editors’ Picks Lyon treble & England heartbreak: The full story behind Lucy Bronze’s dramatic 2019 Liverpool v Man City is now the league’s biggest rivalry and the bitterness is growing Megan Rapinoe: Born & brilliant in the U.S.A. A Liverpool legend in the making: Behind Virgil van Dijk’s remarkable rise to world’s best player Arsenal are, however, very much in the top-four picture, safely through to the quarter-finals of the Carabao Cup and the last-32 of the Europa League and preparing to open their FA Cup campaign with a third round clash against Nottingham Forest.With there plenty of other avenues to explore for his side, Wenger is prepared to forget about chasing the top-flight crown for now, telling reporters: “At the moment we have different worries than the title.”We are too far from the title at the moment to speak about the title. It’s not realistic. Let’s try to win our next game and over a longer distance see if we can come back.”Mathieu Debuchy ArsenalArsenal’s next game comes against Southampton on Sunday.That contest represents another quick turnaround for the Gunners, with kick-off at St Mary’s set for noon.Wenger’s side were in Europa League action on Thursday evening against BATE and the Frenchman believes rivals are getting preferential treatment from those in charge of fixture scheduling.He said: “I have nothing against the fact that we have to do that, as long as our opponents have the same recovery days.”That was not the case last week and will not be the case again. Between three days and five days is a big gap on the recovery side. If we have to play every day I don’t mind as long as our opponents do as well.” Check out Goal’s Premier League 2019-20 fantasy football podcast for game tips, debate and rivalries.last_img read more

Read More

Here Are The Announcers For The New Year’s Day Games

first_imgohio state quarterback dwayne haskinsINDIANAPOLIS, INDIANA – DECEMBER 01: Dwayne Haskins Jr. #7 of the Ohio State Buckeyes throws a pass down field in the game against the Northwestern Wildcats in the second quarter at Lucas Oil Stadium on December 01, 2018 in Indianapolis, Indiana. (Photo by Andy Lyons/Getty Images)While the two College Football Playoff semifinals are over, there is still a ton of great college football to be played before bowl season ends. The next 48 hours are going to be awesome.Tuesday, New Year’s Day, there are five games on the slate. Let’s take a look at the game time, channel and announcers for each of the games.Up first, No. 18 Mississippi State will take on Iowa in an Outback Bowl matchup of 8-4 teams. The Bulldogs and Hawkeyes will kick off at Noon on ESPN. The announcers on the call will be Mark Jones, Dusty Dvoracek and Molly McGrath.There are two games that kick off an hour later. The first is No. 11 LSU vs. No. 8 UCF in the Fiesta Bowl. That game will be broadcast on ESPN and will feature Steve Levy, Brian Griese and Todd McShay.The other is No. 12 Penn State vs. No. 14 Kentucky in the Citrus Bowl. That contest will be broadcast on ABC with Dave Flemming, Brock Huard and Laura Rutledge on the call.The two later games are easily the best of the day. The Rose Bowl, between No. 6 Ohio State and No. 9 Washington, will kick off at 5:00 PM ET on ESPN. Chris Fowler, Kirk Herbstreit and Maria Taylor will be calling that one.Lastly, No. 5 Georgia will take on No. 15 Texas in the Sugar Bowl. That games will kick off at 8:45 PM ET and will be carried on ESPN. Sean McDonough, Todd Blackledge and Holly Rowe will be doing that one.It should be a great New Year’s Day of football. Get excited.last_img read more

Read More

‘England Can’t Chase’: Cricketing fraternity reacts to Australia defeat

first_img Next ‘England Can’t Chase’: Cricketing fraternity reacts to Australia defeatEngland vs Australia, World Cup 2019: England’s dismal performance which resulted in heavy defeat to Australia, triggered a wave of reactions across Twitter, trolling Eoin Morgan and his team.advertisement India Today Web Desk LondonJune 26, 2019UPDATED: June 26, 2019 09:44 IST James Vince was bowled by Jason Behrendorff. (Reuters Photo)England were totted as one of the hottest pre-tournament favourites to reach the semi-finals but 3rd defeat in 7 matches have the hosts in a bit of tricky spot in World Cup 2019.Before the World Cup 2019, England were known for their aggressive brand of cricket and having earmarked match-winners, specific to the ODI format under the leadership of Eoin Morgan.England fans were rejoicing their team’s pre-tournament favourites tag with the famous theme song,It’s coming home’ launched during football World Cup in Russia where the Three Lions lost the semi-finals. The Barmy Army’ were sure that Captain Morgan’s men will reach the distance this time.But England’s second consecutive defeat in the quadrennial event, have left them in a must-win situation from here on. They now need to win at least one of their remaining two matches against New Zealand and India to give themself a fair chance of making the knockouts.On Tuesday, Australia defeated England by 64 runs at Lord’s to become the first team to enter the semi-finals of the 2019 Cricket World Cup. After Aaron Finch smashed a classy 100, Jason Behrendorff picked 5 for 44 and Mitchell Starc finished with 4 for 43 as England failed to chase 286.Former cricketers and fans came down heavily on Eoin Morgan’s side after they failed on the big stage against Australia.England were awful at Lord’s today. Not sure what’s going on but fear it is nerves/panic rather than lack of talent or form.Worried about the World Cup & even more worried about the Ashes… the Aussies will be like a pack of hunting dogs after this. @HomeOfCricket #ENGvAUS pic.twitter.com/BZ5GHoGSIEadvertisementPiers Morgan (@piersmorgan) June 25, 2019England Can’t Chase #CWC19 #EngvAusAakash Chopra (@cricketaakash) June 25, 2019England should do the honourable thing and blame their batting on Rabada’s IPL stint. #ENGvAUSPavilion Opinions (@pavilionopinion) June 25, 2019England in deep waters. Stuck at 8 points. Beaten comprehensively by Australia.Upcoming matches are against India and New Zealand. Huge task and pressure games!!#ENGvsAUS #CWC19Shoaib Akhtar (@shoaib100mph) June 25, 2019These two photos have the same energy. #ENGvAUS #CWC19 pic.twitter.com/kOd5OIHdooPrakash Shetty (@kitneka) June 25, 2019Curtains !!!Michael Vaughan (@MichaelVaughan) June 25, 2019The England captain stepping to square leg when Starc bowled his first delivery to him made me think England could have a little problem over the next week or so.I hope not, but I’ve not seen a captain show such a weakness for a while…Kevin Pietersen (@KP24) June 25, 2019Overwhelming favourites, now gasping to stay alive in a World Cup so many thought was theirs to own! #England #ENGvsAUSHarsha Bhogle (@bhogleharsha) June 25, 2019Also Read | Really? Excellent: Eoin Morgan responds to Kevin Pietersen’s criticism post Australia defeatAlso Read | Not Australia, England probably still World Cup 2019 favourites: Jason BehrendorffAlso See:For sports news, updates, live scores and cricket fixtures, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for Sports news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted bySaurabh Kumar Tags :Follow World Cup 2019Follow England VS AustraliaFollow Eoin Morganlast_img read more

Read More

Community Spirit Recognized With Awards

first_img “These communities are comprised of countless volunteers who come together to preserve and enhance the quality of life for all their members,” said Lt.-Gov. J.J. Grant. “I am delighted to honour the people and places that have such a positive impact on the whole of our province.” Wallace’s application, submitted by Warren Hebb, highlighted the community’s response to a fire that destroyed the only gas station in the area, its local history and year-round festivals. “What sets Wallace apart is its attitude and approach to challenges,” said Mr. Hebb. “The community just gets things done.” Velma MacEachern nominated Ballantynes Cove/Cape George because of the heritage museum, fire department, heritage trails, and various fundraisers that bring her community together. “We are a community with a small population but we work hard together to recognize our history, tradition, culture and heritage,” said Ms. MacEachern. “We are very proud and co-operate to keep our community clean, attractive and welcoming to visitors who come from all over the world.” Living in harmony with the land, respecting the local environment and supporting the younger generation that make up the majority of Rose Julian’s 450-person community of Paqtnkek Mi’kmaw Nation, was highlighted in her application. “The Paqtnkek Mi’kmaw Nation is committed to improving the physical, spiritual, emotional, cultural and mental well-being of the entire community,” said Ms. Julian. “The region’s youth have a strong voice and contribute greatly to the sense of culture and pride. Cherished elders pass on their wealth of knowledge to community youth who grow up honouring the experiences elders remember from days gone by.” The Department of Communities, Culture and Heritage co-ordinates the award. Applicants who best fit the award’s criteria are chosen by an independent selection committee. “This award celebrates the diverse and vibrant communities that are the foundation of our province and gives profile and formal recognition to the ways their residents work together to make life better for Nova Scotian families,” said Communities, Culture and Heritage Minister Leonard Preyra. Communities selected for the Lieutenant Governor’s Community Spirit Award will be honoured at upcoming community celebrations. Lt.-Gov. Grant will attend to present an original piece of Nova Scotian Crystal etched with a representation of each community’s story. For more information, visit communityspiritaward.ca . Three communities in the province are being recognized by the lieutenant governor for their exceptional efforts to create vibrant, welcoming and healthy places to live. In March, Nova Scotians nominated their communities for the Lieutenant Governor’s Community Spirit Award. This year’s recipients are: Ballantynes Cove/Cape George, Antigonish Co. Paqtnkek Mi’kmaw Nation, Antigonish Co. Wallace, Cumberland Co. last_img read more

Read More

Sarah Palins husband files for divorce

first_imgWashington: The husband of former US vice-presidential candidate, Sarah Palin, is reported to have filed for divorce after 31 years of marriage, media reports said. Todd Palin, in a document filed in Anchorage, Alaska, Superior Court, cited an “incompatibility of temperament” in his marriage to Sarah Palin “such that they find it impossible to continue to live together as husband and wife”. The divorce filing and court records used only initials to refer to the pair, with Todd Mitchell Palin listed as TMP and Sarah Louise Palin only identified as SLP, according to the US media. Also Read – Saudi Crown Prince ‘snubbed’ Pak PM, recalled jet from US The Palins, both 55, married in 1988 and have five children together. Friday’s filing included a child custody jurisdiction affidavit for the family’s youngest child, who is 11. Reports say that the couple has sought joint custody. Sarah Palin was Governor of Alaska from 2006 till 2009 and shot to prominence when she became Republican Senator John McCain’s running mate in the 2008 presidential election, which he lost to Barack Obama. Since then, she appeared in several reality TV shows along with Todd Palin — a commercial fisherman and oil field worker. The Palins also faced notable attention, at times unflattering, in past several years. Also Read – Record number of 35 candidates in fray for SL Presidential polls Bristol Palin, who was pregnant during her mother’s vice presidential campaign when she was 17, was featured in MTV’s “Teen Mom OG” in 2018. But she announced her exit from the show in April, saying, “It took away my peace”. In 2018, the Palins’ oldest child — 30-year-old Track Palin — was arrested on domestic violence charges, to which he pleaded not guilty. He had earlier pleaded guilty to criminal trespassing in a dwelling after being accused of breaking into his parents’ home and assaulting Todd Palin. Sarah Palin also has a lucrative career as a public speaker and published two bestselling books. She championed the grassroots Republican Tea Party movement and was also a vocal supporter of US President Donald Trump during his 2016 presidential campaign.last_img read more

Read More

Ivorian poll passes off in democratic atmosphere despite tension – UN envoy

Y. J. Choi, the Special Representative of the Secretary-General and head of the United Nations peacekeeping force in Côte d’Ivoire (UNOCI), said the UN mission was “encouraged to note that along all the five observation routes it established, representatives of both candidates were present in all the polling stations.”Secretary-General Ban Ki-moon, in a statement issued by his spokesperson, noted that by exercising their right to vote, the people of Côte d’Ivoire had demonstrated their desire for peace and stability, and urged the two candidates and their political parties to abide by the law in the resolution of any disputes that might arise.Incumbent President Laurent Gbagbo was pitted against former prime minister Alassane Ouattara in the run-off poll, which followed the first round of the election on 31 October.“As was the case on the day after the first round, the moment has come to safeguard the result. I have no doubt that the will of the Ivorian people, as expressed yesterday, will be respected. I also have no doubt that no candidate will resort to undemocratic means to express his position on the result of the poll,” Mr. Choi said.He stressed that the transportation of the tally sheets is going on normally despite countless rumours, suspicion and false alarms, noting that the tally sheets from the region of Abidjan, which has about a third of the electorate, are in the process of being transported to the headquarters of the Independent Electoral Commission (IEC), without any incident.“I invite everyone to have confidence in the IEC so that it can begin announcing the provisional results of yesterday’s election without delay. It is evident that we are now in a crucial phase that we are going to go through with serenity, confidence, firmness and hope,” Mr. Choi said.He reassured the Ivorian people that they have a reliable partner in the international community, and that UNOCI will continue to support the country in its efforts to end the political crisis.Mr. Ban also called on both candidates to “play their part in maintaining a calm environment and to accept the proclaimed and certified results in a spirit of peace and reconciliation.”“The Special Representative of the Secretary-General will continue, in the context of his certification mandate, all his efforts to safeguard the electoral process so that the will of the Ivorian people will be respected,” the Secretary-General said. “The United Nations will provide its full support to the completion of the electoral operations and to the Ivorian peace process as a whole,” he added.The elections, originally scheduled for as far back as 2005 and repeatedly postponed, are a major step in restoring stability in the country, which was split by civil war into a Government-held south and rebel Forces Nouvelles-controlled north in 2002.On Saturday, youths supporting the opposition demonstrated in Abidjan’s northern suburb of Abobo after the Government declared a curfew. The protest degenerated into clashes with the security forces, resulting in the burning of a police vehicle and the death of three people among the demonstrators, Mr. Choi said.Cote 29 November 2010The run-off presidential elections in Côte d’Ivoire yesterday proceeded “in a democratic atmosphere” despite tension and violent incidents that left three people dead, the United Nations envoy to the West African country said today, calling for calm as the provisional results are awaited. read more

Read More

Key foreign currency quotations

Quotations for key foreign currencies in terms of the Canadian dollar. Quotations are nominal, for information purposes only.Canadian dollar value on Wednesday, the previous day, three-months and one-year: Currency Wed Tue 3 months Year U.S. dollar 1.2771 1.2666 1.2507 1.3352 British Pound 1.6924 1.6640 1.6319 1.6270 Japanese Yen 0.0112 0.0111 0.0112 0.0128 Euro in U.S. 1.1803 1.1765 1.1667 1.0890 Euro in Cdn 1.5073 1.4901 1.4592 1.4540Quotations provided by the Bank of Canada

Read More

UNESCO condemns murder of two journalists in Ecuador

“Such crimes are not only an offence against individuals, but an attack on society as a whole,” UNESCO Director-General Koïchiro Matsuura said in a statement. “I am appalled by the repetition of two such heinous crimes in 24 hours, and I trust that the authorities will spare no effort in bringing the culprits to justice.” José Luis León Desiderio, a presenter on Radio Minutera, was shot dead near his home in Guayaquil, southwestern Ecuador, on the night of 13 to 14 February. According to Reporters Without Borders, he exposed the scale of criminality in Guayaquil in his radio programme.Freelance photographer Saúl Suárez Sandoval, who contributed to the dailies La Hora Durandeña and La Prensa de Durán, was shot dead on 14 February 2006 in Durán, a suburb of Guayaquil.Mr. Matsuura’s statement was the latest in a long series of condemnations he has issued recently over attacks on journalists around the world. UNESCO’s mandate includes the defence of freedom of expression and press freedom. read more

Read More

Bay sees luxury US retailer Saks as global brand with stores in

MONTREAL – Hudson’s Bay Co., which has signed a deal to buy Saks Fifth Avenue, is looking at expanding the U.S. luxury retailer with possible stores in Europe and Asia.“We’d be one of the first to have a department store as a global brand,” HBC president Bonnie Brooks said Monday following a speech to the Canadian Club of Montreal.Brooks, who spent 11 years revitalizing Hong-Kong-based retailer Lane Crawford before joining the Bay in 2008, said Asia holds the greatest potential for global growth.“Europe is certainly a possibility but Asia is more logical,” she told reporters.“It (Saks) has a niche that’s special and that has been well publicized in films for decades and it has a lot of sex appeal.”Brooks, the voice of the Bay’s radio advertising, said the first priority once the US$2.9-billion acquisition closes this year will be to open seven Saks stores in Canada.The timing for the Canadian store openings is still being worked out, but Brooks said they could come within two years.Brooks said at least one of the Saks Fifth Avenue stores will be located in Quebec, where she said “fashion-forward shoppers” are more familiar with the upscale brand than U.S. rival Nordstrom, which plans to open its first store in Canada next year.Hudson’s Bay will also open about 20 Saks Off Fifth Ave. outlet stores in Canada in addition to the full-sized department stores.And the company (TSX:HBC) also plans a couple more Hudson’s Bay outlets.Brooks said the acquisition of Saks gives HBC access to different shoppers with its Saks, Lord & Taylor and Hudson’s Bay stores.Analyst Patricia Baker of Scotia Capital said a recent restructuring at HBC that includes bringing Marigay McKee from Harrods to head Saks is positive.“The company will be able to better maintain the unique identity of each retail brand, while ensuring each is managed in an efficient manner that aligns to HBC’s corporate goals,” she wrote in a report.Saks operates 42 stores across the U.S. and 70 Off Fifth Ave. locations, while HBC’s holdings include 90 Hudson’s Bay stores and 69 Home Outfitters in Canada.HBC also owns 48 Lord & Taylor classic retail stores in the U.S. by Ross Marowits, The Canadian Press Posted Sep 23, 2013 6:18 pm MDT AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email Bay sees luxury U.S. retailer Saks as global brand with stores in Asia, Europe read more

Read More

Restrictions unmet promises unbridled violence in Sudan a recipe for disaster says

“It is essential there are prompt, transparent and independent investigations into how all these people lost their lives, as well as into the causes of such a large number of injuries,” said the High Commissioner.Ms. Bachelet also urged the authorities to respect people’s right to protest peacefully and, as desired by much of the population and the African Union (AU), which is trying to broker a deal, to ensure a swift transition to a civilian government..@UNHumanRights High Commissioner Michelle Bachelet urges #Sudan to restore freedoms, investigate violations and move swiftly to civilian rule.Proper investigations into all acts of violence and allegations of excessive use of force, must be launched.https://t.co/gN6dsmMgcx pic.twitter.com/iygbaG6rve— UN Geneva (@UNGeneva) July 3, 2019 In response to the Sudan Professionals Association’s (SPA) call to support a civilian-led transitional authority following April’s military takeover, mass protests reportedly took place in more than ten major towns and cities, including Khartoum, Omdurman, Kassala, Gadaref, Madani, Port Sudan, Atbara, El Fasher, Nyala, Zalingie and Kosti, Despite the Transitional Military Council’s (TMC) total shutdown of the internet on 10 June, the scale and breadth of Sunday’s protests appear to have been unprecedented in recent Sudanese history, according to the UN rights office, OHCHR.Mounting causalitiesMs. Bachelet said her office had received numerous allegations that excessive force had been used by security forces against protestors. She recounted that a senior Health Ministry official had reportedly pinned the blame on protesters for the deaths of seven people, and injuries to 181 others, during Sunday’s demonstrations. The SPA-affiliated Sudanese Doctors Central Committee also reported that live bullets were allegedly fired by the paramilitary Rapid Support Forces (RSF) and other security forces in Omdurman and Atbara. And on Monday morning, the tortured bodies of three local activists were found in Khor Abu Anga in Omdurman, ratcheting up the death toll to at least ten since the start of Sunday’s massive protests. Hospital attacksMs. Bachelet said she was especially disturbed by reports of hospital attacks, including that joint RSF, security and police forces had chased protestors inside of the Gadaref city hospital, firing live ammunition and tear gas. OHCHR said allegations had been made that police and RSF – which consists of many former Janjaweed fighters from Darfur – had raided the Al-Tabib hospital in Khartoum and pursued protestors into the military hospital in Omdurman, firing tear gas and live bullets – shooting dead a medical employee. “The RSF were alleged to have been heavily implicated in the mass violations in early June,” said Ms. Bachelet. “The fact that no serious action has been taken to investigate what happened then, and further in the past, simply feeds the belief that members of the RSF and other security forces have carte blanche to do what they want to protestors and other people”. The UN rights chief noted that earlier calls for investigations into the killings, attacks on medical facilities and thousands of reported rapes and sexual assaults that took place since 3 June had gone unheeded and that her 7 June offer to deploy a UN human rights monitoring team to examine allegations of human rights violations had gone unanswered. It is essential there are prompt, transparent and independent investigations into how all these people lost their lives — UN human rights chief“This is a completely unacceptable situation and the Transitional Military Council has an obligation to ensure that members of the security forces are held accountable for any crimes they commit”, she underscored.She acknowledged the TMC’s 27 June offer to release prisoners of war as a welcome gesture but regretted that the 30 June handover deadline had not been met. “This recipe of restrictions, unmet promises, and bouts of unbridled violence which are neither investigated nor punished is stoking massive resentment – as Sunday’s protests showed all too clearly,” Ms. Bachelet said. “If things continue like this, it will be a recipe for disaster.”The UN human rights chief said the authorities must issue clear instructions to all security forces not to use force against peaceful protestors, noting that firearms are prohibited, unless there is imminent risk of life or serious injury. read more

Read More

The CelticsWizards Series Is Tight The Teams Defenses Are Not

FiveThirtyEight Embed Code More: Apple Podcasts | ESPN App | RSS | Embed Welcome to the latest episode of Hot Takedown, FiveThirtyEight’s sports podcast. On this week’s show (May 9, 2017), we’re joined by FiveThirtyEight’s Chris Herring to break down the latest news from the NBA playoffs as we edge closer and closer to the conference championships. We discuss Celtics vs. Wizards and the sweeps by the Cavaliers and the Warriors. Next, the Mets have had a wild week, but is their injury-ridden squad cursed? Finally, FiveThirtyEight’s Christie Aschwanden returns to fill us in on the attempts to run a two-hour marathon. Plus, a significant digit on Ryan Howard.You can check FiveThirtyEight’s latest NBA predictions, which are updated after every game.The Ringer’s Jonathan Tjarks says the Celtics-Wizards series has been a game of coaching Whac-A-Mole.In his latest piece, FiveThirtyEight’s Chris Herring takes a look at Draymond Green’s defensive prowess.Chris also wrote about how Isaiah Thomas, the shortest guy in the NBA, became unstoppable.Rob Arthur wrote about the Mets’ unremarkable injury woes.FiveThirtyEight’s latest MLB predictions (updated after every game) currently give the Mets a 38 percent chance of making the playoffs.FiveThirtyEight’s Christie Aschwanden shared some thoughts on Eliud Kipchoge’s attempt to run a two-hour marathon. He came tantalizingly close.Significant Digit: .184, Ryan Howard’s batting average for the Atlanta Braves’ Triple-A Gwinnett team. Howard was released from his contract on Monday after 11 games. read more

Read More

South Africas Mineral Resources Minister dodges addressing the Mining Charter

first_imgMineral Resources Minister Mosebenzi Zwane dodged the industry’s most pressing issue when he opened the Investing in African Mining Indaba in Cape Town yesterday by ignoring the brewing Mining Charter controversy. Rather, he used the platform to commend the industry for returning to growth in 2017 and indicated the sector had significantly contributed to the economy in the latter part of the year following a technical recession. He also highlighted the government’s investment into geological mapping and emphasised its value to potential investors.Deloitte Africa Mining lead Andrew Lane says while 2017 saw improvements for the South African and global mining industry, Minister Zwane should not take credit for the upswing.“That can be attributed to the increase in commodity prices. Given that South Africa’s investor-friendly reputation has been slightly tarnished, it was hoped he would make an announcement on the Mining Charter,” Lane says.While Minister Zwane has publicly stated he is open to bilateral discussion with investors, there has been no concrete guidance on the charter, itself subject to a court battle. Lane says Minister Zwane also focused the beneficiation benefits discussion on downstream opportunities, ignoring the upstream opportunities.“There are several upstream lateral and second and third-order beneficiation opportunities surrounding mining, but the government is fixated on the downstream ones. While downstream manufacturing assists industrialisation, South Africa cannot lay it at the feet of the mining industry – manufacturing is a manufacturing problem and attracting those investors requires cultivating an appealing environment,” he says.In the Q&A session later in the afternoon Minister Zwane avoided the question regarding the MPRDA, rather referring to his open-door policy. Zwane stated that he is open to a “bosberaad” and willing to engage with stakeholders. Lane remarks, however, that the sentiment within the industry is that regardless of the open-door policy their concerns are not being sufficiently addressed.Lane says the industry acknowledges and supports the government’s intent to diversify ownership and the importance of junior mining. However, the industry depends on the large mining companies for their capital and skills, and the investment environment should recognise this reality, otherwise they will seek friendlier recipients.“Given the lack of tangible announcements on the charter, it will be interesting to see how the government enforces regulations when the market is expecting both that document and its responsible minister to change,” Lane concludes.last_img read more

Read More

VIST Robotics on mine automation present and future

first_imgAnton Potapov, CTO, VIST Robotics (now a subsidary of ZYFRA Group) recently gave his take on the near term trends on automation in mining. A few years ago, world mining leaders launched a large-scale process of updating their own fleets of equipment. Acumen Research and Consulting (ARC) estimates that the global mining equipment market will reach $285.5 billion worldwide by 2026. “At the same time, the main drivers of the growth will be automated technologies and so-called ‘smart’ solutions for the production. Already now the most advanced ‘miners’ perform a number of technological processes, such as drilling and transportation of raw materials, with the use of robotics, while in 2019 the majority of industry players may start using new technologies on an industrial scale.”Analysts at Technavio predict the growth of the robotics market in the mining industry by an average of 27.01% by 2022. “On the very eve of the New Year, transnational mining and metallurgical company Rio Tinto, which was one of the first to build its own ‘mine of the future’, officially announced the launch of the world’s first AutoHaul autonomous long-distance railway network for the transportation of iron ore to the ports of the company in the Pilbara Region in Western Australia. The company’s ten-year work on the creation of the largest railway robot should lead to an increase in the ore production in Pilbara from 340 million to 360 million tonnes.”At the same time, in the other hemisphere, Swedish technology companies, including Ericsson, Scania, Epiroc and SKF, are joining together in the Swedish Mining Automation Group (SMAG) and are beginning to promote their own products and technologies for mining companies. Sweden is currently not among the top mining countries, and therefore SMAG started its cooperation with Canadian companies that hope in the short term to upgrade their own production and to start using the innovative technology with the help of the concern.“In 2019, manufacturers of industrial robotics will increasingly resort to international cooperation to expand the market and introduce new technological solutions in mining. At the same time, the leading players in the robotics market should be ready for the increased competition and emergence of new companies that have not previously worked in the mining sector. A few years ago, there was practically no alternative in the market of unmanned trucks, such companies as Caterpillar and Komatsu fully met the needs of miners in autonomous transport. In 2018, the Swedish automaker Volvo signed an agreement with the Norwegian mining company Brønnøy Kalk, according to which Volvo unmanned trucks will carry limestone on a three-mile route between the mine and the port. It is planned that in 2019 the system will operate to the full extent.”In Morocco, a Terex mining truck with robotic control developed by VIST Robotics has passed successful trials at a special test site at the operations of phosphate miner OCP. In Russia, autonomous BELAZ trucks are already being used by Siberian coal and energy company SUEK in Khakassia. At the moment, the first robot dump truck has been assembled and successfully passed along the route of the mine haulage in an offline mode, while the process of assembling and equipping a second dump truck, as well as building the infrastructure necessary for the operation of autonomous machines is being carried out. In Kazakhstan, VIST Robotics together with the Nazarbayev University started to work on the truck tractor based on the KAMAZ NEO truck. In addition to unmanned trucks, the company is testing a robotic drilling system. It is planned that the developed product will replace a person in particularly dangerous production conditions, while the cost of drilling wells will remain at the same level or even decrease. The company expects to see the first test results in the second quarter of 2019.“Companies engaged in the development of unmanned aerial vehicles can also start to increase production, as mining companies are finding new and new applications for drones. Drones are most actively used for the exploration and testing of equipment in hard-to-reach places. Drones make 3D maps of the fields, which are then analysed using Big Data technologies to assess the potential of the mine. Unmanned aerial vehicles help to avoid emergency situations in the quarries, tracking the process of explosive operations and traffic.”Australian mining giant BHP Billiton, known for its active introduction of drones into production, announced the beginning of using drones in sea freight in the experimental mode. The company intends to use drones to check the status of the holds of vessels before flights. Unmanned vehicles will replace the person and will independently record meter readings, look for the damage that cannot be seen with the naked eye and transmit the image in the 4K format to the operator. The expansion of the use of robotic and automated technologies in the mining industry is made possible by reducing the cost of innovative products.According to a McKinsey report, over the past 30 years, the average price of a robot has fallen by half in real terms, and even more in relation to labour costs. Analysts believe that demand from emerging economies encourages robot manufacturers to switch to cheaper regions, and robotics will continue to fall in price. Mines, which will use only robots, which will be controlled by robots, are no longer a fantasy. In 2019, one of the first of such projects may be implemented.Resolute Mining announced that its gold mine Syama in Mali will be the first in the world to become fully autonomous. A fibre-optic network will be created throughout the mine, ensuring constant contact of autonomous tractors, robot drillers and ground-based control centres. “A report of the consulting company BDO Australia says that by 2020, more than 50% of miners around the world will be replaced by robots. Such forecasts sound very encouraging for manufacturers of industrial robotics and at the same time impose a great responsibility on the companies that will need to develop more advanced technical solutions to fully replace people. Manufacturers of robotic equipment also have to pay special attention to the protection of devices after massive virus attacks on industrial facilities in 2018. BDO Australia analysts believe that by 2020, activist hackers will launch at least five global cyberattacks with permanent denial of service (PDO) at mines through connected devices.”He concludes: “Not less and perhaps more significant obstacle to the final transition to the use of robotics in mining is still the problem of employment of workers whose work is being performed by the machine. Governments cannot allow unemployment to rise, even though the costs of production automation have been reduced. There is a difficult situation, as the contradictions between effective business and social responsibility in the coming year will only grow. Only a joint effort of states, mining companies and manufacturers of robotics will help to find a way that will suit all players in the industry.”last_img read more

Read More

Former MakerBot COO creates the worlds first 500 3D printer

first_imgAt first glance Sam Cervantes and his latest invention may seem questionable, but after spending some time talking with him I’m sure what he’s showing off is legit. Cervantes and his team are working on the first $500 3D printer, a device known as the Solidoodle. At the risk of sounding cliche, what you’re witnessing in the video is truly game-changing; the Solidoodle is a significant step towards making 3D printing accessible to the average consumer.By now you have heard all about 3D printing and have had the opportunity to drool over the possibilities. Most likely the only thing that has been keeping you from purchasing one for your own home is the price tag, which before the announcement of the Solidoodle would be in the neighborhood of $2000 when all is said and done. Sure, it’s the same price as a high-end MacBook Pro, but it’s a considerable chunk of change for what essentially is at this point a toy for grown-up geeks.During his time in the industry, Cervantes took a look at this fact and decided it was one of the last barriers to break through to allow the technology to move forward through crowd-sourced innovation. He decided that he could design a low-cost 3D printer for the masses and help to get a device in as many people’s hands as possible, and with that came the birth of the Solidoodle. Striking out on his own, using his personal bank account, Cervantes formed his new company and gathered a team of six like-minded engineers to begin prototyping his vision.While many people know Cervantes as the former COO of MakerBot, his expertise in engineering and manufacturing processes runs much deeper. He previously worked at GE as an aerospace engineer designing the engine for the 747 and was employed by two different 3D printing companies, so he has the experience to lead a project with the goal of smashing through the cost barrier that exists for an infant technology. By applying his knowledge of making quality parts for the lowest cost possible, Cervantes and his team were quickly able to assemble their first working prototypes that led to the Solidoodle.By using an Arduino and open-source software for the 3D modeling the Solidoodle team was able to construct a printing device that makes 6x6x6-inch models out of melted plastic filament. While that’s not an very large work space, it’s certainly enough to let you express your imagination. The printing is done by one extrusion head working from the map provided by the software, creating each model layer-by-layer, as it typical with today’s 3D printers. For building materials the company currently recommends using ABS filament, but is working on adapting the device to make use of polylactic acid based or PLA filament. The upside to using PLA is that it’s made from corn, which of course is available in abundance in America. It’s conceivable that as the 3D printing industry grows, you could be replenishing your filament supply with locally grown corn.The Solidoodle looks to be a solidly made piece of equipment. This is reinforced by Cervantes’ claim that a 200-pound person could stand on top of the device — while it’s printing — and not cause any damage.To answer the big question — how could the Solidoodle base model only cost $499?“We didn’t cut corners if that’s what you’re asking,” Cervantes said when I asked him, “We simply started with a clean sheet of paper when it came to designing an affordable 3D printer, and built it from the ground up. We stripped away anything that we didn’t think was necessary to create a machine that does one thing: make 3D prints.”Cervantes went on to talk about how he and his team leveraged the knowledge and experience from their collective backgrounds to slim down the production process to avoid muddying the waters when it came to quality components. What was key for the project was the fact that the whole team was committed to the simple vision of creating a printing device for the masses, rather than just the enthusiasts.Much like your probably felt when you first watched the video at the top of the post, I was skeptical about Solidoodle as a whole. When I asked Cervantes about the lack of credibility the homemade video he released had he replied, “You can tell by the video we created that we aren’t marketers, we’re engineers and tech people that are focused on the “back room” if you will, making things work and getting excited about what we can accomplish.” He assured me that a more professional video was going to be made, but that right now his goal was to make sure all of the pre-orders that have been placed will be filled. While this was certainly reassuring about the veracity of the Solidoodle project, it was the conversation Cervantes and I had at the end of the interview that convinced me that the device isn’t only legit but one of the most exciting that I have seen in a while.Cervantes made it clear that his goal was to do whatever it takes to get a Solidoodle into the hands of anyone who wants one. He has a clear understanding that for technology to move forward at an explosive pace that it must be first accepted and then adopted by consumers, so it must be both useful and easy to use. When talking with him, I was struck not only by how intelligent he is but also by the fact that he’s a pretty humble and non-assuming guy. From the video, you can tell that he’s uncomfortable being the center of attention, something that is refreshing in this day and age of every executive trying to be the next Steve Jobs.Cervantes sees the future of the market depending on getting the younger generation’s hands actually on these machines so they can begin to dream big about what can happen with them. He was describing to me the vision beneath the Solidoodle vision, an altruistic motivation that is both admirable and acts like a magnet drawing people into sharing the dream of having this technology being a major part of everyday life in the world.While Cervantes is certainly capable of thinking in large, abstract terms, he’s fully aware that Solidoodle is simply a step towards seeing 3D printing becoming a new standard for consumers. Currently, he’s aware that the device has a very limited scope in creating useful items, as displayed above when a young lady decides that she wants to test a carabiner that came off a Solidoodle while using a rock wall. The results are certainly humorous, but also serve as a reminder to the Solidoodle team that they desperately need other people to get involved to dream up new ways of creating items using the technology they’ve helped to develop.Which leads to how you can get your very own Solidoodle to experiment with. As mentioned before, you can pre-order a unit for $499, this model comes without a door or case which are just for aesthetics (the process isn’t dangerous unless you stick your hand inside while it’s operating). Cervantes stated that right now after ordering and payment it takes six to eight weeks to build your device and ship it out to you. While this may seem like a long time, know that it comes to you fully assembled, meaning you open it up and start playing right away. You can also decide to drop an extra $100 and get some nice accessories like an interior light, cabinet and door and spool holder to allow you to do other things while the unit is printing. That’s still a great price for a 3D printer in your home.You can check out a gallery of images of the Solidoodle below. Let us know if you purchase one, we want to see what you are doing with your new toy!Solidoodle – houseSolidoodle – houseSolidoodle – part 001Solidoodle – building 005Solidoodle – plate 003Solidoodle – building 002Solidoodle – buildingSolidoodle – plateSolidoodle – sideSolidoodle – 003Solidoodle – turnedSolidoodle – openlast_img read more

Read More

SIDA les nouveaux antirétroviraux efficaces chez les porteurs du VIH en échec

first_imgSIDA : les nouveaux antirétroviraux efficaces chez les porteurs du VIH en échec thérapeutiqueDes chercheurs de l’INSERM sont parvenus à démontrer l’efficacité des antirétroviraux mis au point ces dernières années chez les porteurs du VIH en échec thérapeutique. Autrement dit, chez les malades pour qui les classes de médicaments habituelles n’étaient pas efficaces. C’est une découverte importante et un espoir pour tous les malades porteurs du VIH. Dans la revue The Lancet datée du 10 octobre, des chercheurs français de l’INSERM ont réussi à démontrer l’efficacité des nouveaux antirétroviraux chez les patients qui présentent une résistance aux autres molécules. En effet, cela fait plus de vingt ans maintenant que les antirétroviraux sont utilisés pour freiner le développement de la maladie, grâce à leur capacité de contrôler la réplication du VIH dans l’organisme. Aujourd’hui, il existe ainsi plusieurs classes de ces médicaments sur le marché. Malheureusement, elles ne sont pas efficaces chez tous les porteurs du virus. À lire aussiSIDA : 10 symptômes qui doivent alerterCes dix dernières années, les chercheurs se sont donc appliqués à créer de nouvelles molécules pour tenter d’améliorer la santé de ces patients “résistants”. C’est pourquoi l’équipe du Professeur Dominique Costagliola, directrice de l’unité “Epidémiologie, stratégies thérapeutiques et virologies cliniques dans l’infection à VIH” de l’hôpital de la Pitié Salpétrière, a décidé de s’intéresser à l’efficacité de ces nouvelles molécules. Pour cela, elle a analysé des données recueillies entre 2000 et 2009 sur 2.476 patients traités à partir de 1998. Des sujets en échec pour les trois classes historiques d’anti-VIH : les inhibiteurs nucléosidiques de la transcriptase inverse (INTI),  les inhibiteurs non-nucléosidiques de la transcriptase inverse (INNTI) et les inhibiteurs de la protéase (IP). Des molécules qui s’attaquent toutes aux composants du virus qui lui permettent de se répliquer.Une réduction de la charge virale En vérité, les sujets étudiés constituaient 3% de 24 cohortes participant au projet PLATO II, lui-même inclus dans la collaboration de cohortes européennes COHERE (Collaboration of Observational HIV Epidemiological Research Europe). Une étendue qui a permis d’augmenter la puissance de l’étude. Au final, les chercheurs ont alors observé que la charge virale, autrement dit la quantité de virus contenue dans le sang, est devenue indétectable pour trois fois plus de patients. De même, la survenue d’évènements cliniques correspondant au SIDA a été divisée par quatre. Des résultats positifs attribués aux progrès médicaux réalisés durant cette période.En dix ans, les médicaments sont devenus plus simples d’utilisation, plus efficaces mais aussi mieux tolérés par les malades. Ils présentent également peu de résistance croisée avec les antirétroviraux disponibles auparavant. L’équipe du Pr Costagliola souligne ainsi les bénéfices issus de l’introduction de nouveaux médicaments pour lutter contre le SIDA, qui affecte aujourd’hui plus de 30 millions de personnes à travers le monde.  Le 11 octobre 2011 à 16:12 • Maxime Lambertlast_img read more

Read More

Mark Zuckerberg should resign as CEO says exFacebook security chief

first_img Internet Services Tech Industry Former Facebook security chief Alex Stamos says Mark Zuckerberg has too much power as CEO. Sportsfile/Corbis via Getty Images Facebook’s former security chief says Mark Zuckerberg has amassed too much power and should resign as chief executive officer of the social networking giant.”There’s a legit argument that he has too much power,” Alex Stamos said at the Collision Conference in Toronto on Tuesday. “He needs to give up some of that power. If I was him, I would go hire a new CEO for the company.”Finding someone to run the company would allow Zuckerberg to turn his attention to building products, Stamos said in comments first reported by CNBC. Stamos, who left the company in 2018, even has a suggested replacement in mind: Microsoft President Brad Smith.Product is “where his passion is,” Stamos said. “He should hire a CEO that can help signal both internally and externally that the culture has to change.”Zuckerberg and Facebook have been grappling with a series of privacy and security issues over the last year, including the Cambridge Analytica scandal, concerns about disinformation and struggles over moderating its platform. The social network has attracted the scorn of lawmakers, and expects a fine of up to $5 billion for its privacy violations. Stamos is well acquainted with the subject, having played a central role in Facebook’s response to interference on its platform by Russian trolls in the 2016 US presidential election. He also has a reputation for confronting other company leaders about challenging privacy issues. Facebook has experienced rapid growth in recent years, fueled by acquisitions, including Instagram and WhatsApp, a messaging service. Critics have also argued that Facebook’s enormous power needs to be kept in check. Chris Hughes, who co-founded Facebook with Zuckerberg while they were students at Harvard, said in a New York Times op-ed earlier this month that Zuckerberg has too much power and called for the social network to be broken up. 5:10 Tags Calls to break up Facebook aren’t new, but Stamos argued that such a move wouldn’t solve issues such as disinformation campaigns or manipulating ad targeting for political purposes.”There’s a lot of excitement for antitrust because it feels good to be like ‘I hate this company, so let’s break it up,'” Stamos said. “Having three companies that have the same fundamental problems doesn’t make anything better.”Facebook didn’t immediately respond to a request for comment. Share your voice Comments Facebook co-founder: Time to break up the social network 3 Now playing: Watch this: Mark Zuckerberg Facebooklast_img read more

Read More

US and Italy trained snipers to guard LoC ahead of infiltration season

first_imgIndian Troops guarding the LoC {Representational Image}ReutersThe Line of control (LoC) running along with Pakistani border is all set to get elite units of the Indian Army equipped with deadly new sniper rifles. The elite units of the Indian Army have received special training from American and Italian experts.In recent times, especially after Balakot air strikes, Pakistani rangers have been violating ceasefire on an almost daily basis and targeting Indian posts without any provocation. Sniping has become a major challenge for Indian troops along the 778-km long LoC as the Pakistani Army is better equipped with modern Remington modular sniper rifles as well as better training.Until now, the Indian Army was using the Russian made 7.62mm Dragunov semi-automatic sniper rifles, which have a comparatively limited kill range of 800-metre but the new additions would mean that the Army would be able to take out targets at over 1,000 metres with precision. The specially trained units armed with the Beretta .338 Lapua Magnum Scorpio TGT and the Barrett .50 calibre M95 is going to give a much-needed boost to the forces guarding LoC.As per a report published in The Print, the units equipped with these deadly snipers have been deployed near LoC before the infiltration season which is likely to kick-off very soon. A BSF jawan on patrol along the fence on the Line of Control (LoC).ReutersSnipers made to killFirst manufactured in 1995, the American Barrett M95 sniper is an anti-material rifle which has an effective range of 1,800 metres. The anti-material rifle is special in terms that it can pierce through metal hence increasing the lethality.Special Forces across the Armies prefer using Barrett M95 sniper, which is bolt action sniper rifle fitted in 12.7×99mm Browing Machine Gun cartridge. Its lighter weight and compactness is one of the most striking features as it weighs around 10kg when unloaded; moreover, it comes with a five-round detachable box magazine.The other rifle which is being secured by the Indian Army for its troops guarding borders is the Victrix Armaments .338 Lapua Magnum Scorpio TGT, manufactured by Italian firm Beretta. The rifle uses 8.6×70mm, Lapua Magnum with a rimless, bottle-necked, centre-fire rifle cartridge.Launched in the mid-1980s, this high powered, long-range cartridge was used in the Afghanistan war and the Iraq war. The rifle was initially made to penetrate armour at nearly 1000 meters, over the years its effective range has been increased to 1,500 metres and beyond.last_img read more

Read More